In a small bowl, whisk together the warm water, sugar, and dry yeast. Let it rest until the yeast start to foam on top, 5-10 minutes.
In a large bowl, combine the flour, salt, garlic powder, and oregano. Stir them together and then make a well in the center of the dry mixture.
Pour the foamed-up yeast mixture and the olive oil in the dry mixture well. Use a rubber spatula to slowly bring together the dry and wet ingredients. Stir until the dough comes together and it can be shaped into a ball.
Stir until the dough comes together and it can be shaped into a ball. It helps to drizzle a little olive oil on top of the dough and use your hand to push the dough down and then fold it onto itself 3-4 times to develop the gluten.
Once the dough is shaped into a ball, it should still be tacky. Place in a olive oil coated bowl and cover the bowl with a clean cloth. Let the dough rest for 10-15 minutes.
Making the Pepperoni Pizza Muffins
Once the dough has rested, divide the dough into 12 equal parts. Use your hand to shape each piece into a ball.
Lightly coat the muffin tin cavities with olive oil. Place each ball of dough, smooth side up, in the muffin tin. Cover with the clean cloth and let the dough rise in a place for 20 minutes.
Preheat the oven 400F.
When the dough balls have risen just over the top of the muffin tin, top them with the marinara sauce, cheese and pepperoni slices.
Place the prepared pizza muffins in the preheated oven. Place a sheet pan on the rack underneath the muffin pan, in case there are any drips. Bake for 20 minutes.
Remove the baked Pizza Muffins from the oven and let them cool down until they can be removed from the tin.